Oslo Randomized Laparoscopic Versus Open Liver Resection for Colorectal Metastases Study

Prospective Randomized Study of Laparoscopic Versus Open Liver Resection for Colorectal Metastases

The purpose of the study is to compare outcomes of laparoscopic versus open liver resection for colorectal metastases in a prospective and randomized study. The study will include all non-anatomic liver resections in our institution.

The primary end point is that the use of laparoscopic technique significantly can reduce the frequency of complications to liver resection. Secondary end points are 5-year survival, immediate surgical outcomes, quality of life and degree of impairment of the immune system.

Full protocol is published open access in Trialsjournal:

http://www.trialsjournal.com/content/16/1/73

Inclusion Criteria:

• Patients eligible for radical liver resection without formal liver resection or without assistance of radiofrequency ablation

Exclusion Criteria:

• Inability to give written informed concent
• Patients with tumors that can't be resected without reconstruction of vessels or bile ducts
• Patients with tumors that can't be resected without 1)formal liver resection 2)combination with radiofrequency ablation
• Patients with extrahepatic metastasis except resectable metastasis in lungs and adrenals
• Pre- and peroperative diagnosis of non radically treatable disease