Diet and Exercise in Type 2 Diabetes - a Randomized Controlled Trial

Diet and Exercise in Type 2 Diabetes - a Randomized Controlled Trial

The investigators investigate if combined progressive aerobic training and resistance training improve metabolic control and fat mass in patients with type 2 diabetes who are eating a modified paleolithic diet. The investigators randomize 40 participants to two groups: 1) Modified paleolithic diet and exercise under observation 3 sessions/week, 2) Modified paleolithic diet and general advice about exercise.

The investigators primary hypothesis is that in patients with type 2 diabetes decreases fat mass more with progressive exercise under observation and a modified paleolithic diet than with general advice about exercise and a modified paleolithic diet.

Inclusion Criteria:

• type 2 diabetes less than 10 years
• BMI 27-35
• women only after menopause
• diabetes treatment with diet and/or metformin
• HbA1c between 45 and 94

Exclusion Criteria:

• nicotine use
• insulin
• betablockers
• estrogens orally
• blod pressure >160/100
• macroalbuminuria
• malignancy during the past 5 years
• alcoholism
• depression
• cardiovascular disease/stroke
• liver disease
• serious lung disease, GI disease or kidney disease
• more than 30 minutes/5 days a week of moderate exercise during the last 6 months
• resistance training during the past 6 months
• official weight loosing program during the past year
• obesity surgery
• night work
• MADRS-S (Montgomery Asberg Depression Rating Scale) >20 points
• AUDIT >14 points for women, >16 points for men
• not possible to obtain venous sampling