Deep Brain Stimulation for the Treatment of Obesity

Deep Brain Stimulation For Morbid, Treatment-Refractory, Obesity

The purpose of this clinical study is to investigate the safety and efficacy of deep brain stimulation (DBS) as a treatment option for obesity.

The purpose of this clinical study is to investigate the safety and efficacy of deep brain stimulation (DBS) as a treatment option in the management of severe, treatment refractory, morbid obesity.

Inclusion Criteria:

• At least 24 months post Roux-en-Y gastric bypass surgery without evidence of a sustained improvement in BMI after gastric bypass surgery for at least 6 months.
• Participant is willing to comply with all follow-up evaluations at the specified times
• Participant is able to provide informed consent
• Fluent in English

Exclusion Criteria:

• Medical contraindications for general anesthesia, craniotomy, or DBS surgery
• Evidence of neurological disorders, e.g., multiple sclerosis, Parkinson's disease and ischemic stroke, or severe brain atrophy or the presence of subdural hygromas or subdural hematomas.
• Severe cardiovascular, pulmonary, renal, liver, hematological disease, severe coagulopathy, acute infectious process