The aim of this study is to evaluate the efficacy of myo-inositol in preventing gestational diabetes in high risk pregnant women.

Inclusion Criteria:

60 women in their first trimester of pregnancy affected by one or more of the following risk factors:

• Glycemia levels > 92 mg/dl
• BMI > 30
• At least a parent or a brother (or sister)affected by diabetes
• Pre-existing pregnancy with gestational diabetes

Exclusion Criteria:

• Pregnant women affected by pregestational diabetes
• Twin pregnancy
• Patients affected by pre-existing diseases in pregnancy (diabetes excluded)
• Patients affected by chronic disorders