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| ID | Type | Description | Link |
|---|---|---|---|
| 2006-000377-30 | EudraCT Number |
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This trial is conducted in Europe and Oceania. The aim of this trial is to assess the effects of liraglutide on energy intake in subjects with type 2 diabetes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Lira --> placebo | Experimental |
| |
| Placebo --> glim | Placebo Comparator |
| |
| Glim --> lira | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| liraglutide | Drug | 1.8 mg/day injected subcutaneously for 4 weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| The energy intake at a standardised buffet meal with a preload paradigm quantified using Foodworks 2.10 |
| Measure | Description | Time Frame |
|---|---|---|
| The energy intake at a standardised buffet meal without a preload paradigm quantified using Foodworks 2.10 | ||
| Macronutrient distribution of food consumed at a standardised buffet meal with a preload paradigm quantified using Foodworks 2.10 |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Global Clinical Registry (GCR, 1452) | Novo Nordisk A/S | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Novo Nordisk Investigational Site | Adelaide | South Australia | 5005 | Australia | ||
| Novo Nordisk Investigational Site |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22446097 | Result | Horowitz M, Flint A, Jones KL, Hindsberger C, Rasmussen MF, Kapitza C, Doran S, Jax T, Zdravkovic M, Chapman IM. Effect of the once-daily human GLP-1 analogue liraglutide on appetite, energy intake, energy expenditure and gastric emptying in type 2 diabetes. Diabetes Res Clin Pract. 2012 Aug;97(2):258-66. doi: 10.1016/j.diabres.2012.02.016. Epub 2012 Mar 24. |
| Label | URL |
|---|---|
| Clinical Trials at Novo Nordisk | View source |
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| ID | Term |
|---|---|
| D003920 | Diabetes Mellitus |
| D003924 | Diabetes Mellitus, Type 2 |
| ID | Term |
|---|---|
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D009750 | Nutritional and Metabolic Diseases |
| D004700 | Endocrine System Diseases |
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| ID | Term |
|---|---|
| D000069450 | Liraglutide |
| C057619 | glimepiride |
| ID | Term |
|---|---|
| D052216 | Glucagon-Like Peptide 1 |
| D004763 | Glucagon-Like Peptides |
| D052336 | Proglucagon |
| D005768 | Gastrointestinal Hormones |
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| placebo | Drug | Liraglutide placebo, injected subcutaneously for 4 weeks |
|
| placebo | Drug | Glimepiride placebo, dose individually adjusted, administered orally for 4 weeks |
|
| glimepiride | Drug | Dose individually adjusted, administered orally for 4 weeks |
|
| Macronutrient distribution of food consumed at a standardised buffet meal without a preload paradigm quantified using Foodworks 2.10 |
| Total duration of eating at the buffet meal (satiation) |
| Weight |
| Waist circumference |
| Adverse events |
| Neuss |
| 41460 |
| Germany |
| D006728 |
| Hormones |
| D006730 | Hormones, Hormone Substitutes, and Hormone Antagonists |