Not provided
Not provided
Not provided
Not provided
Not provided
Research question was answered by Acta Anaesthesiol Scand 2012; 56: 102-109.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The investigators hypothesize that a spinal anesthetic administered prior to the induction of general anesthesia will result in reduced need for pain medication and reduced postoperative pain, as well as reduced hospital stay following a total abdominal hysterectomy.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| General Anesthesia | Active Comparator |
| |
| General Anesthesia + Spinal Anesthesia | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| General Anesthesia + Spinal anesthesia combined | Drug | All patients will receive a preoperative multimodal analgesic regime:
Patients will receive a spinal anesthetic with:
After the spinal, a general anesthetic will be induced using:
|
| Measure | Description | Time Frame |
|---|---|---|
| Morphine consumption | The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward. | 1 day |
| Total Morphine consumption | The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward. | Post-operative day 1 |
| Total Morphine consumption | The primary outcome will be total opioid use per day, as recorded by the PCA pump and transcribed by the nursing staff in the PACU and on the post-operative ward. | Post-operative day 2 |
| Measure | Description | Time Frame |
|---|---|---|
| Pain score on the VAS | In the PACU: within the first 5 minutes | |
| Pain score on the VAS | In the PACU: after 30 minutes | |
| Pain score on the VAS |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jacelyn Larson, MD, FRCPC | University of Saskatchewan | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Saskatoon City Hospital | Saskatoon | Saskatchewan | S7K0M7 | Canada |
Not provided
| ID | Term |
|---|---|
| D000768 | Anesthesia, General |
| D035061 | Control Groups |
| ID | Term |
|---|---|
| D000758 | Anesthesia |
| D000760 | Anesthesia and Analgesia |
| D015340 | Epidemiologic Research Design |
| D004812 | Epidemiologic Methods |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| General Anesthesia (control group) | Drug | All patients will receive a preoperative multimodal analgesic regime:
Group I (General anesthetic) patients will receive a general anesthetic :
Patients will receive a Morphine PCA as per protocol that will be initiated in the Post Anesthetic Care Unit (PACU). |
|
| In the PACU: after 60 minutes. |
| Pain score on the VAS | Upon arrival on the post-operative ward |
| Pain score on the VAS | On the post-operative ward: after 1 hour |
| Pain score on the VAS | On the post-operative ward: after 4 hours |
| Pain score on the VAS | On post-operative day 1 at 02:00 |
| Pain score on the VAS | On post-operative days 1 at 06:00 |
| Pain score on the VAS | On post-operative days 1 at 10:00 |
| Pain score on the VAS | On post-operative days 1 at 14:00 |
| Pain score on the VAS | On post-operative days 1 at 18:00 |
| Pain score on the VAS | On post-operative days 1 at 22:00 |
| Pain score on the VAS | On post-operative day 2 at 02:00 |
| Pain score on the VAS | On post-operative day 2 at 06:00 |
| Pain score on the VAS | On post-operative day 2 at 10:00 |
| Pain score on the VAS | On post-operative day 2 at 14:00 |
| Pain score on the VAS | On post-operative day 2 at 18:00 |
| Pain score on the VAS | On post-operative day 2 at 22:00 |
| D008919 | Investigative Techniques |
| D012107 | Research Design |
| D008722 | Methods |