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The treatment of postoperative pain continues to be inadequate in the investigators practice setting.
Inadequate pain treatment not only contributes to postoperative complications in the short term but can also be a factor that favors the development of chronic postoperative pain and diminishes long-term quality of life. Risk factors that can lead to a transition to chronic pain need to be analyzed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients who had inguinal herniorraphy. |
| ||
| Patients who had hysterectomy. |
| ||
| Patients who had thoracotomy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Inguinal herniorraphy. | Procedure | Inguinal herniorraphy (non laparoscopic). |
|
| Measure | Description | Time Frame |
|---|---|---|
| Evaluation of chronic postsurgical pain. | After 3 months a physical examination will take place and after 12 months a follow-up will be reported by phone. | After 3 and 12 months of surgery. |
| Measure | Description | Time Frame |
|---|---|---|
| Predictive factors of chronic postsurgical pain. | Preoperative (psychological factors, preoperative pain, pharmacologic treatment) intraoperative (surgical technic, type of anaestesia) and postoperative(posoperative pain, surgical complications and treatment of postoperative pain). | After 3 and 12 months of surgery. |
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Inclusion Criteria:
Exclusion Criteria:
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All spanish patients who undergo scheduled surgery of one of the following types: inguinal herniorrhaphy, hysterectomy, toracothomy.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital Municipal de Badalona | Badalona | Barcelona | 08911 | Spain | ||
| Hospital Universitari Germans Trias i Pujol |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32631293 | Derived | Bande D, Molto L, Pereira JA, Montes A. Chronic pain after groin hernia repair: pain characteristics and impact on quality of life. BMC Surg. 2020 Jul 6;20(1):147. doi: 10.1186/s12893-020-00805-9. | |
| 25985024 | Derived | Montes A, Roca G, Sabate S, Lao JI, Navarro A, Cantillo J, Canet J; GENDOLCAT Study Group. Genetic and Clinical Factors Associated with Chronic Postsurgical Pain after Hernia Repair, Hysterectomy, and Thoracotomy: A Two-year Multicenter Cohort Study. Anesthesiology. 2015 May;122(5):1123-41. doi: 10.1097/ALN.0000000000000611. |
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Sample collection Five milliliters of venous blood will be extracted from each patient with chronic pain; control samples will come from a DNA bank. All patients must have given their written consent to testing and storage.
- Plasma DNA will be extracted with a BioRobot EZ1 Workstation (Qiagen).
| Hysterectomy. | Procedure | Hysterectomy: Vaginal and abdominal. |
|
| Thoracotomy . | Procedure | Thoracotomy (non laparoscopic). |
|
| Badalona |
| Barcelona |
| 08916 |
| Spain |
| Hospital del Mar | Barcelona | Barcelona | 08003 | Spain |
| Hospital de l'Esperança | Barcelona | Barcelona | 08024 | Spain |
| Hospital de la Santa Creu i Sant Pau | Barcelona | Barcelona | 08025 | Spain |
| Hospital Sagrat Cor | Barcelona | Barcelona | 08029 | Spain |
| Hospital Universitari Vall d'Hebron | Barcelona | Barcelona | 08035 | Spain |
| Hospital Clínic i Provincial de Barcelona | Barcelona | Barcelona | 08036 | Spain |
| Hospital del Sant Boi | Barcelona | Barcelona | 08830 | Spain |
| Hospital de San Bernabé | Berga | Barcelona | 08600 | Spain |
| Hospital de Granollers | Granollers | Barcelona | 08400 | Spain |
| Hospital Universitari de Bellvitge | L'Hospitalet de Llobregat | Barcelona | 08907 | Spain |
| Hospital General de Manresa | Manresa | Barcelona | 08240 | Spain |
| Hospital de Mataro | Mataró | Barcelona | 08304 | Spain |
| Hospital Parc Tauli | Sabadell | Barcelona | 08208 | Spain |
| Hospital Mutua de Terrassa | Terrassa | Barcelona | 08221 | Spain |
| Hospital Universitari Mutua de Terrassa | Terrassa | Barcelona | 08227 | Spain |
| Hospital de Viladecans | Viladecans | Barcelona | 08840 | Spain |
| Hospital Universitari Doctor Josep Trueta de Girona | Girona | Girona | 17007 | Spain |
| Hospital de Santa Caterina | Salt | Girona | 17190 | Spain |
| Hospital Santa Maria | Lleida | Lleida | 25198 | Spain |
| Hospital Sant Joan de Reus | Reus | Tarragona | 43201 | Spain |
| Hospital Clínico de Valencia | Valencia | Valencia | 46010 | Spain |
| Hospital General Universitario de Valencia | Valencia | Valencia | 46014 | Spain |
| Hospital Universitari de la Fe | Valencia | Valencia | 46026 | Spain |
| Hospital Lluís Alcanyís de Xàtiva | Xàtiva | València | 46800 | Spain |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| D059350 | Chronic Pain |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D007044 | Hysterectomy |
| D013908 | Thoracotomy |
| ID | Term |
|---|---|
| D013509 | Gynecologic Surgical Procedures |
| D013519 | Urogenital Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
| D019616 | Thoracic Surgical Procedures |
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