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The purpose of our study is to determine whether one injection with plasma into the origin of the plantar fascia is an effective treatment of plantar fasciitis.
90 patients will be randomized into three groups. 30 patients will be treated with one plasma injection, 30 patients will be treated with one injection with saline and 30 patients will do physiotherapy and use heel cups. The two groups who receive injections will do the same physiotherapy and use heel cups, as the conservatively treated group.
Both groups randomized to receive an injection will have a 10 ml blood sample taken from their cubital vein. The sample is centrifuged for 5 minutes at 5000 rpm. No additives are added. 3 ml of plasma i obtained, and the syringe i blinded. Is the patient randomized to receive an injection with saline, a similar syringe is blinded with 3 ml of saline. The injection into to the origin of the plantar fascia i done 10 minutes after the sample of blood is obtained. The content of the syringe i blinded to both the investigator and the patient.
The injection i performed from the medial aspect of the heel under guidance of ultrasound. No local/systemic analgetic is used. The content of the syringe is spread using peppering technique into the origin of the plantar fascia.
Patients will do questionnaires at inclusion and after 1, 2, 3, 6 and 12 months. The questionaires will be Foot Function Index and SF-36 as well as questions about their use of analgetics, use of heel cups and intensity of their physiotherapy
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Plasma | Experimental |
| |
| Saline | Sham Comparator |
| |
| Physiotherapy + heel cap | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Plasma | Biological | 3 ml plasma injected once into the plantar fascia |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Pain on a VAS score |
| Measure | Description | Time Frame |
|---|---|---|
| Disability |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Bjørn Nedergaard, Cand. Med. | Contact | 0045 20204541 | bspn77@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Bjørn Nedergaard, Cand. Med. | Kolding Sygehus | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Sygehus Lillebælt - Kolding Sygehus | Recruiting | Kolding | 6000 | Denmark |
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| ID | Term |
|---|---|
| D036981 | Fasciitis, Plantar |
| ID | Term |
|---|---|
| D005208 | Fasciitis |
| D009140 | Musculoskeletal Diseases |
| D005534 | Foot Diseases |
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| ID | Term |
|---|---|
| D012965 | Sodium Chloride |
| D026741 | Physical Therapy Modalities |
| ID | Term |
|---|---|
| D002712 | Chlorides |
| D006851 | Hydrochloric Acid |
| D017606 | Chlorine Compounds |
| D007287 | Inorganic Chemicals |
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| Saline |
| Biological |
3 ml of saline injected once into the plantar fascia |
|
| Physiotherapy + heel cap | Other | Physiotherapy three times a day for 8 weeks. Heel caps until symptoms are gone |
|
| D017670 |
| Sodium Compounds |
| D013812 | Therapeutics |
| D012046 | Rehabilitation |