Study of a Probiotic Strain to Prevent Mastitis and to Eradicate GBS Colonization

Oral Administration of a Probiotic Strain to Pregnant Women: Effects on the Prevention of Lactational Mastitis and on the Eradication of GBS Colonization

In previous studies, the investigators have seen that carefully-selected Lactobacillus strains are a good alternative to antibiotics for the treatment of lactational mastitis. The objective of this new study is to check if they can also have a preventive role when administered to women with a history of mastitis with one or more previous infants. Since the investigators have also realized that peripartum antibiotherapy (mainly GBS-targeting intrapartum prophylaxis)is a predisposing factor for mastitis (because of the selection of resistant bacteria), the investigators would also like to test if administration of the strains to GBS-colonized pregnant women may lead to GBS eradication. Therefore, a mastitis-predisposing factor would de avoid.

Inclusion Criteria:

• Normal pregnancy
• Healthy women
• Lactational mastitis in, at least, a previous lactation period
• No symptomatic vaginal infections

Exclusion Criteria:

• Any kind of health problems related to pregnancy
• Symptomatic vaginal infections
• Allergy to cow's milk protein
• Intolerance to lactose
• Antibiotic treatment