Acetic Acid Chromoendoscopy to Judge Gastric Intestinal Metaplasia

Acetic Acid Chromoendoscopy for Judging Extent of Gastric Intestinal Metaplasia

The presence and the extent of gastric intestinal metaplasia(IM) is a good indicator of high risk group of gastric cancer. Many methods was developed to survey it, including multiple gastric biopsy or methylene blue chromoendoscopy. But they are not practical in the routine screening exam, limited by cost and accessibility. Spraying of acetic acid is commonly used in screening cervical cancer, to induce whitish discoloration of metaplastic mucosa. The investigators have confirmed such whitish discoloration is induced in gastric IM, with accuracy > 80% in a pilot study of the investigators. This prospective study will tell the accuracy, sensitivity and specificity of acetic acid chromoendoscopy for judging gastric IM.

Inclusion Criteria:

• Person who undergo gastroduodenoscopy
• Person who visit Konyang University Hospital

Exclusion Criteria:

• Bleeding diathesis
• History of stomach neoplasms
• History of upper gastrointestinal surgery