Pharmacokinetics Ertapenem Burns

Pharmacokinetics of Ertapenem When Used in Empiric Treatment in Burn Patients. Prospective Open Label Study.

This study will examine the pharmacokinetics of ertapenem in ventilated badly (> 30% SCT) burn patients.

Inclusion Criteria:

• Patients aged 18 to 70 years
• Burned on 30 to 60% of their body surface
• Mechanical ventilation
• Hospitalized in the intensive care unit of Nantes University Hospital for less than 8 days.
• Which the family gave consent
• insured

Exclusion Criteria:

• Patients whose family refused to sign the consent for participation.
• Patients allergic to beta lactam
• Patients with renal failure with creatinine clearance <80 ml.mn-1
• Pregnant women
• Persons protected by the law