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| ID | Type | Description | Link |
|---|---|---|---|
| Dry Eye 1 | Other Identifier | Zagreb University Hospital Eye Department, Zagreb, Croatia |
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Purpose:
To establish whether there is a correlation between dry eye symptoms, age and gender, a difference in symptom intensity in different times of the day, which test (Schirmer or TBUT) better correlates with dry eye symptoms, whether it is possible to reliably use cheap, easy to use hygrometer in everyday clinical setting, and finally whether there is statistically significant correlation between applied tests (TBUT, Schirmer and evaporimetry).
Methods:
Subjects: 45 in group without dry eye related symptoms, and 45 in group with symptoms.
Examination included structured case history (questionnaire), slit lamp examination with fluorescein staining, periocular evaporimetry, TBUT test and Schirmer test.
Purpose:
The purpose of this study was to establish whether there is a correlation between dry eye symptoms, age and gender, any difference in symptom intensity in different times of the day, which test (Schirmer or TBUT) better correlates with dry eye symptoms, whether it is possible to reliably use cheap, easy to use hygrometer in everyday clinical setting, and, finally, whether there is statistically significant correlation between applied tests (TBUT, Schirmer and evaporimetry).
Methods:
Subjects were divided in two groups: 45 in group without dry eye related symptoms, and 45 in group with symptoms.
Examination was performed in the following sequence:
Case history consisted of the following questions:irritation more pronounced on wind? irritation during reading and/or watching TV or computer? irritation more pronounced during winter? gritty sensation in the eyes? irritation more pronounced in the morning or evening? All answers, except to the last question, were graded from 0 (no complaints) to 3 (severe).
Evaporimetry was performed using commercially available hygrometer from HYGROTEC (Titisee-Neustadt, Germany), installed in swimming goggles with its front part sawn off.
First measurement was performed by measuring for 5 minutes with eyes closed. Second measurement also lasted 5 minutes, with eyes kept open, normal blinking, and with subject fixating at one point in distance, with no eye movements.
Measured parameters included:
basal φ (%): relative environment humidity before measurement basal T: environment temperature before measurement closed eye φ (%): relative humidity in front of closed eye open eye φ (%): relative humidity in front of open eye C/O: ratio of φ (%) closed/open eye
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Patients without dry eye symptoms | Patients without dry eye symptoms as measured by standard questionnaire. |
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| Patients with dry eye symptoms | Patients with dry eye symptoms as measured by standard questionnaire. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Only measurements done on subjects in both groups. | Other | As study compared specific diagnostic procedures, no intervention was done or compared. |
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| Measure | Description | Time Frame |
|---|---|---|
| Tear evaporation | Five minutes of tear evaporation measurement with eyes closed and five with open, normal blinking. | 10 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of tear evaporation to symptoms score | Tear evaporation measurement compared to dry eye symptoms score (0-15 points). | 15 minutes (10 minutes tear evaporation, 5 minutes symptoms score recording) |
| Comparison of tear evaporation to Tear Film Break-up Time (TBUT) |
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Inclusion Criteria:
Exclusion Criteria:
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Patients were volunteers who came for a standard ophthalmological exam in Zagreb University Hospital Eye Clinic, and whose enrollment was based on convenience sampling.
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| Name | Affiliation | Role |
|---|---|---|
| Igor Petricek, MD, PhD | Zagreb University Hospital Eye Department, Zagreb, Croatia | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Zagreb University Hospital Eye Department | Zagreb | HR-10000 | Croatia |
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| ID | Term |
|---|---|
| D015352 | Dry Eye Syndromes |
| ID | Term |
|---|---|
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
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Comparison of tear evaporation to Tear Film Break-up Time (seconds). |
| 15 minutes (10 minutes evaporation measurement, 5 minutes TBUT measurement) |
| Comparison of tear evaporation to Schirmer test | Comparison of tear evaporation to Schirmer test (mm) | 15 minutes (10 minutes tear evaporation measurement, 5 minutes Schirmer test) |
| Comparison of tear evaporation to corneal staining | Comparison of tear evaporation to corneal staining using fluorescein (score 1-3): 1:5-10 corneal stains at six o'clock; 2: 10-25 corneal stains; 3: more than 26 diffuse corneal stains | 12 minutes (10 minutes tear evaporation measurements, 2 minutes corneal staining assessment) |
| Comparison of tear evaporation to conjunctival hyperemia | Comparison of tear evaporation to conjunctival hyperemia (score 1-3): 1: minimal; 2: moderate; 3: severe | 11 minutes (10 minutes evaporation measurement, 1 minute conjunctival hyperemia assessment) |