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| Name | Class |
|---|---|
| Shanghai Children's Medical Center | OTHER |
| Shanghai, China | UNKNOWN |
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The purpose is to determine if the consumption of study product has an effect on acute respiratory infections and/or diarrheal disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cow's Milk | Placebo Comparator | Powdered whole cow's milk |
|
| Follow-On Formula | Experimental | Powdered Follow-On Formula with added long-chain Polyunsaturated fatty acid, prebiotics, and polysaccharide |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cow's milk | Dietary Supplement | Powdered whole cow's milk |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Acute respiratory infections and diarrheal disease | 28 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Allergic manifestations | 28 weeks | |
| Systemic antibiotic use | 28 weeks | |
| Duration of acute respiratory infection and diarrheal disease |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Xingming Jin, M.D. | Professor of Development and Behavioral Pediatrics, Shanghai Children Medical Center | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Shi-ji-xing Child Care Center, Jin Dong District | Jinhua | Zhejiang | 321000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 24843061 | Derived | Li F, Jin X, Liu B, Zhuang W, Scalabrin D. Follow-up formula consumption in 3- to 4-year-olds and respiratory infections: an RCT. Pediatrics. 2014 Jun;133(6):e1533-40. doi: 10.1542/peds.2013-3598. Epub 2014 May 19. |
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| ID | Term |
|---|---|
| D008892 | Milk |
| ID | Term |
|---|---|
| D001628 | Beverages |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D003611 | Dairy Products |
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| Follow-On Formula |
| Dietary Supplement |
Powdered Follow-On Formula with added long-chain Polyunsaturated fatty acid, prebiotics, and polysaccharide |
|
| 28 weeks |
| Changes in stool patterns | Baseline and 28 weeks |
| Fecal immune markers | Baseline and 28 weeks |
| Serum Ferritin status | Baseline and 28 weeks |
| Incidence of stool parasites | Baseline and 28 weeks |
| Growth | 28 weeks |
| Adverse events | The incidence of any adverse event for each participant | 28 weeks |
| Acceptance of study product | Acceptance of study product based on quantity consumed. | 28 weeks |
| Serum immune markers | Baseline and 28 weeks |
| Serum zinc status | Baseline and 28 weeks |
| D005502 |
| Food |
| D019602 | Food and Beverages |