Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The aim of the study is to evaluate whether the TEP-CT can be sensitive and specific in identifying degenerated intraductal papillary mucinous tumor of the pancreas.The results will be compared to those obtained by the pathological analysis of the removed piece of pancreas.
Before surgery is undertaken, a 18 fluoro-deoxy-glucose positrons emission tomography combined with computed tomography (18-FDG TEP-CT ) will be performed. The primary outcome of this study is to compare results of the TEP-CT with those obtained by the pathological analysis of the removed piece of pancreas.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| positrons emission tomography | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 18 fluoro-deoxy-glucose positrons emission tomography combined with computed tomography | Other | 18 fluoro-deoxy-glucose positrons emission tomography combined with computed tomography |
| Measure | Description | Time Frame |
|---|---|---|
| Specificity of TEP-CT to point out malignant lesions in pancreas, the gold standard being the anatomopathological analysis of the piece of pancreas removed during the surgery. | TEP-CT of the different 5 parts of the pancreas (head, uncus, isthmi, body and tail) will be interpreted by nuclearity Doctors. TEP-CT will be considered positive if there is a pathological fixation of the 18-FDG , defined as any focal or diffuse fixation of 18-FDG above the background level of fixation in the pancreas. The anatomopathological analysis of the piece of pancreas removed during the ablative surgery will be considered as positive if the degree of dysplasia seen for each part of the pancreas is "infiltrating carcinoma". Results will then be compared in term of specificity. | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Sensitivity of TEP-CT to point out malignant lesions in pancreas, the gold standard being the anatomopathological analysis of the piece of pancreas removed during the surgery. | TEP-CT of the different 5 parts of the pancreas (head, uncus, isthmi, body and tail) will be interpreted by nuclearity Doctors. TEP-CT will be considered positive if there is a pathological fixation of the 18-FDG , defined as any focal or diffuse fixation of 18-FDG above the background level of fixation in the pancreas. The anatomopathological analysis of the piece of pancreas removed during the ablative surgery will be considered as positive if the degree of dysplasia seen for each part of the pancreas is "infiltrating carcinoma". Results will then be compared in term of sensitivity. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHU Nord | Amiens | France | 80080 | France | ||
| Maison de Haut Lévêque CHU |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 3 months |
| Comparison of specificity of the TEP-CT to detect malignant lesions in pancreas versus specificity of conventional devices, the gold standard being the anatomopathological analysis results | Result of conventional devices (such as computed tomography, magnetic resonance cholangiopancreatography or endoscopic ultrasound) will be considered positive if diagnosis is "malignant lesion" or "probable malignant lesion". The 5 parts of the pancreas will be examined. | 3 months |
| Number of patients for which metastasis will be detected through TEP-CT and confirmed by biopsy and/or conventional specific device | 3 months |
| Bordeaux |
| France |
| 33604 |
| France |
| Hôpital Beaujon APHP | Clichy | France | 92110 | France |
| Hôpital C Huriez | Lille | France | 59037 | France |
| Hospices Civils de Lyon | Lyon | France | 69437 | France |
| Institut Paoli Calmettes | Marseille | France | 13273 | France |
| CHU Nord | Marseille | France | 13915 | France |
| CHU | Nantes | France | 44093 | France |
| CHU Hôpital Pontchaillou | Rennes | France | 35033 | France |
| Hôpital de Hautepierre | Strasbourg | France | 67098 | France |
| Hôpital St-Antoine | Paris | 75012 | France |
| CHU Rangueil | Toulouse | 31059 | France |
| ID | Term |
|---|---|
| D009369 | Neoplasms |
Not provided
Not provided
Not provided