In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients

In Vivo Measurement of Corneal Epithelial Changes in Dry Eye(DE) Patients

The purpose of this study is to measure corneal epithelial changes in dry eye subjects using a novel lubricant eye gel.

The purpose of this study is to measure corneal epithelial changes in dry eye (DE) subjects using a novel lubricant eye gel.

Inclusion Criteria:

Subjects must have history of dry eye as determined by:

1. Questionnaire
2. Tear Film Break Up Time less than or equal to 10 seconds
3. Schirmer's score of less than or equal to 5 mm
4. Corneal staining greater than or equal to 3 in either eye, and
5. Positive for conjunctival staining (greater than or equal to 1)

Exclusion Criteria:

• Patients cannot wear contact lenses within 1 week prior nor during the study, and cannot have a history of hypersensitivity to any component of Systane Gel Drops.