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Prolongation of mechanical ventilation poses serious personal and financial threats to healthcare consumers.
The investigators objectives are create and implement an multidisciplinary evidenced-based ventilator-weaning protocol to assess whether a systematic approach compared with the physician's judgment only decreases time spent on the ventilator, complications of mechanical ventilation and length of stay in critical care unit.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Protocol-directed | Experimental | Discontinuation of ventilation was based in multidisciplinary protocol. |
|
| Usual care | No Intervention | Discontinuation of ventilation was left entirely to the discretion of the physicians. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Multidisciplinary weaning-ventilator protocol | Other | We implemented a multidisciplinary protocol for weaning from mechanical ventilation.This consist of a daily screening for readiness, performing a spontaneous breathing test, evaluation of signs of intolerance and decision on extubation. |
| Measure | Description | Time Frame |
|---|---|---|
| Mortality | length of ICU stay (days) | |
| Duration of Weaning From Mechanical Ventilation | days | |
| Duration of Mechanical Ventilation | days | |
| Length of Intensive Care Unit Stay | days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Liliane Barbosa da Silva Passos | Federal University of Uberlandia | Principal Investigator |
| Thulio Marquez Cunha | Federal University of Uberlandia | Study Chair |
| Carlos Henrique Alves de Rezende, MD | Federal University of Uberlandia | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Federal University of Uberlandia | Uberlândia | Minas Gerais | 38400-902 | Brazil |
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Adult patients hospitalized in the intensive care unit, remained on mechanical ventilation for more than 24 hours and subjected to weaning from mechanical ventilation.
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| ID | Title | Description |
|---|---|---|
| FG000 | Protocol-directed | Discontinuation of ventilation was based in multidisciplinary protocol. |
| FG001 | Usual Care | Discontinuation of ventilation was left entirely to the discretion of the physicians. |
| Title | Milestones | Reasons Not Completed | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Care Usual |
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| Protocol |
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| ID | Title | Description |
|---|---|---|
| BG000 | Protocol-directed | Discontinuation of ventilation was based in multidisciplinary protocol. |
| BG001 | Usual Care | Discontinuation of ventilation was left entirely to the discretion of the physicians. |
| Units | Counts |
|---|---|
| Participants |
|
| Title | Description | Population Description | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Denominator Units Selected | Denominators | Classes |
|---|---|---|---|---|---|---|---|---|---|
| Age Continuous | Mean |
| Type | Title | Description | Population Description | Reporting Status | Anticipated Posting Date | Parameter Type | Dispersion Type | Unit of Measure | Calculate Percentage | Time Frame | Units Analyzed | Denominator Units Selected | Arm/Group Information | Denominators | Classes | Analyses | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Primary | Mortality | Overall | Posted | Number | participants | length of ICU stay (days) |
|
|
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| ID | Title | Description | Deaths (Affected) | Deaths (At Risk) | Serious Events (Affected) | Serious Events (At Risk) | Other Events (Affected) | Other Events (At Risk) |
|---|---|---|---|---|---|---|---|---|
| EG000 | Protocol-directed | Discontinuation of ventilation was based in multidisciplinary protocol. |
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The lack of sedation protocol in the intensive care unit.
| Title | Organization | Phone | Extension | |
|---|---|---|---|---|
| Liliane Barbosa da Silva Passos | Federal University of Uberlândia | 553432182150 | lilibsp@yahoo.com.br |
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|
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| NOT COMPLETED |
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| BG002 | Total | Total of all reporting groups |
| years |
|
| Sex: Female, Male | Count of Participants | Participants |
|
| Region of Enrollment | Number | participants |
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| Primary | Duration of Weaning From Mechanical Ventilation | overall | Posted | Mean | Standard Deviation | days | days |
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| Primary | Duration of Mechanical Ventilation | Not Posted | days |
| Primary | Length of Intensive Care Unit Stay | Not Posted | days |
| 0 |
| 0 |
| 0 |
| 0 |
| EG001 | Usual Care | Discontinuation of ventilation was left entirely to the discretion of the physicians. | 0 | 0 | 0 | 0 |
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