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Cobedding consists of associating twins in a common cocoon in order to maintain links developed in utero and reduce the stress of premature birth. The aim of this randomized, controlled prospective study is to compare efficacy (in term of newborn daily weight gain) and safety of cobedding versus single-bedding of preterm twins.
Randomization will occur during the first 96 hours after birth.Twins randomized in the cobedding arm will be kept in the same cocoon until maximum 37 amenorrhea weeks. Each day, parameters (weight gain, …) will be registered.At two years old, neuromotor development of twins will be estimated by Brunet-Lezine test.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Cobedding | Active Comparator | Newborn twins are settled in a single bed : this is cobedding |
|
| Single -bedding | Placebo Comparator | Newborn twins are settled in two beds : this is single-bedding |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Cobedding | Procedure | Newborn twins are settled in a singe bed: this is cobedding |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Daily weight gain of cobedded preterm twins versus that of single-bedded preterm twins | The main objective of this study is to compare daily weight gain of cobedded preterm twins versus that of single-bedded preterm twins | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| cardiorespiratory stability | cardiorespiratory stability | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| Thermoregulation |
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Inclusion Criteria:
Exclusion Criteria:
Inclusion criteria not fulfilled
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universitary Hospital Center | Nantes | Loire atlantique | 44093 | France |
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| Single-bedding |
| Procedure |
Newborn twins are settled in two single beds : this is single-bedding |
|
Thermoregulation
| patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| parents well-being estimated through questionnaires | parents well-being estimated through questionnaires | 5 weeks |
| newborns comfort | newborns comfort | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| stop date of parenteral nutrition | stop date of parenteral nutrition | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| date of removal of central catheter | date of removal of central catheter | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| date of removal of nasogastric catheter | date of removal of nasogastric catheter | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| stop date of oxygenotherapy | stop date of oxygenotherapy | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |
| neuromotor development estimated by "Brunet Lezine" test at 2 years old | neuromotor development estimated by "Brunet Lezine" test at 2 years old | 2 years |
| Hospitalization time length | Hospitalization time length | patients will be followed for the duration of hospital stay in special bed (cobedding or single bed) , an expected average of 5 weeks |