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This study aims to identify the relationship between a low-sodium diet and neurohormonal and clinical status in stable chronic HF patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| low-sodium diet | Experimental | (1500 mg daily) |
|
| moderate-sodium diet | No Intervention | sodium (100 mmol or 2300 mg daily; Usual Care) |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| low-sodium diet (1500 mg daily) | Other |
|
| Measure | Description | Time Frame |
|---|---|---|
| composite clinical outcomes | (cardiovascular hospitalizations, emergency department visits due acute decompensated HF, and all-cause mortality) in patients with stable HF | 12 months |
| Measure | Description | Time Frame |
|---|---|---|
| symptoms and quality of life | improves symptoms and quality of life for patients with stable HF | 12 months |
| reduces natriuretic peptide levels | reduces natriuretic peptide levels |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Justin Ezekowitz, MBBCh MSc | University of Alberta | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Alberta | Edmonton | Alberta | T6G 2B7 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28531423 | Derived | Colin-Ramirez E, McAlister FA, Zheng Y, Sharma S, Ezekowitz JA. Changes in dietary intake and nutritional status associated with a significant reduction in sodium intake in patients with heart failure. A sub-analysis of the SODIUM-HF pilot study. Clin Nutr ESPEN. 2016 Feb;11:e26-e32. doi: 10.1016/j.clnesp.2015.11.002. Epub 2015 Dec 29. |
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| ID | Term |
|---|---|
| D006333 | Heart Failure |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D004039 | Diet, Sodium-Restricted |
| ID | Term |
|---|---|
| D004035 | Diet Therapy |
| D044623 | Nutrition Therapy |
| D013812 | Therapeutics |
| D004032 | Diet |
| D009747 |
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| 12 months |
| Nutritional Physiological Phenomena |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |