Comparison of Methods to Facilitate Rapid Sequence Intubation

Comparison of Mg, Ketamine, Large Dose Rocuronium, and Priming on Intubating Condition in Rapid Sequence Intubation

In this study, methods which are known for facilitating rapid sequence intubation or accelerating rocuronium (Roc)onset are compared including magnesium (Mg), ketamine pretreatment, large dose rocuronium and priming.

Patients are pretreated with Mg, ketamine, or priming dose Roc. Two groups do not receive pretreatment, but are given Roc 0.6 mg/kg or 0.9 mg/kg.

Inclusion Criteria:

• age 18 - 65 years,
• ASA 1 - 2,
• patients scheduled for elective surgery under general anesthesia,
• BMI 18.5-24.9 kg/m2
• Mallampati class I-II

Exclusion Criteria:

• neuromuscular disorder,
• cardiac/hepatic/renal insufficiency,
• pregnant.
• anticipated difficult airway
• medications that influence neuromuscular transmission