This is a retrospective study that follows the clinical evolution, the pregnancy and the post-partum perioad of female patients with Congenital Myasthenic Syndrome.

The aim of this study is to better understand the action of hormonal factors that are presumably incriminated for the fluctuation of the disease. The investigators would also like to better adress the issues of women with Congenital Myasthenic Syndrome, who desire a pregnancy : the possibility of decompensation, the problems that can arise during the course of the childbearing, the risk of foetal malformations.

Inclusion criteria:

• Adult women
• Congenital myastenic syndrome genetically confirmed or with clinical compatible and electrophysiological evidence
• Written consent

Exclusion Criteria:

• Neurological or general pathology occurs significantly with the initiation and conduct of a pregnancy.

Women with Congenital Myasthenie Syndrome