Probiotic Sport Study

Impact of Supplementation With Probiotics on Exercise-induced Oxidative Stress and Endotoxemia in Trained Men

We investigate the impact of a probiotic-based dietary supplement on oxidative stress and endotoxemia before and after strenuous exercise.

Hypotheses (H1):

• Supplementation has an influence on oxidative stress parameters before and post exercise
• Supplementation has an influence on parameters of endotoxemia and inflammation before and post exercise
• Strenuous exercise has an influence on parameters of oxidative stress, inflammation and endotoxemia

Inclusion Criteria:

• trained men
• 30 - 45 years
• non-smokers
• 4wk wash out of all dietary supplements

Exclusion Criteria:

• untrained people (VO2max < 55 ml x kg-1)
• female
• all people not matching this age group
• smokers
• all men taking dietary supplements
• all men that fail in ergometric exercise eligibility testing, refering to the standards in sports medicine (e.g.: significant ST-decrease or increase, blood pressure > 240 mmHg, tachycardia, polymorphic extrasystolia, cyanosis, bradyarrhythmia..)
• all people that are not adjudged as "Healthy"