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We investigate the impact of a probiotic-based dietary supplement on oxidative stress and endotoxemia before and after strenuous exercise.
Hypotheses (H1):
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| probiotic-based dietary supplement | Active Comparator |
| |
| placebo | Placebo Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| probiotic-based dietary supplement | Dietary Supplement | 24 trained men receive a probiotic-based dietary supplement for 16 weeks. Dosage 3x 10-9 per day |
|
| Measure | Description | Time Frame |
|---|---|---|
| markers of oxidative stress, endotoxemia and inflammation | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Manfred Lamprecht, PhD PhD | Medical University of Graz | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Medical University of Graz | Graz | 8010 | Austria |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22992437 | Derived | Lamprecht M, Bogner S, Schippinger G, Steinbauer K, Fankhauser F, Hallstroem S, Schuetz B, Greilberger JF. Probiotic supplementation affects markers of intestinal barrier, oxidation, and inflammation in trained men; a randomized, double-blinded, placebo-controlled trial. J Int Soc Sports Nutr. 2012 Sep 20;9(1):45. doi: 10.1186/1550-2783-9-45. |
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| ID | Term |
|---|---|
| D007249 | Inflammation |
| D019446 | Endotoxemia |
| ID | Term |
|---|---|
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D016470 | Bacteremia |
| D018805 | Sepsis |
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|
| placebo | Dietary Supplement | 24 trained men receive a placebo for 16 weeks with same dosage compared to active group |
|
|
| D007239 |
| Infections |
| D014115 | Toxemia |
| D018746 | Systemic Inflammatory Response Syndrome |