Surgical Resection Lowers Oxidative Stress Markers in Patients With Colorectal Cancer

Surgical Resection Lowers Oxidative Stress Markers in Patients With Colorectal Cancer

Study of Oxidative stress Markers (F2 Isoprostanes for lipid peroxidation, Carbonyl groups for protein peroxidation, 3 Nitrotyrosine for damage by nitrogens, and 8-Hydroxyguanosine for RNA peroxidation)in patients with colorectal cancer undergo surgical treatment (preoperatively during the intervention and postoperatively) and controls.

Study of the impact of surgery on Lipid peroxidation, Protein peroxidation, damage by nitrogens, and RNA peroxidation, in patients undergo surgical resection for colorectal cancer and compared with controls, and validation of the responsiveness of oxidative stress markers on surgery

Inclusion Criteria:

• Patients with colorectal cancer
• Controls

Exclusion Criteria:

• ASA>3
• Metastatic Disease
• Acute bowel obstruction
• Acute bowel perforation
• BMI<30
• Chronic Systemic or Autoimmune Diseases
• Smokers
• Alcohol consumers