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| Name | Class |
|---|---|
| City Hospital No 41, Ekaterinburg, Russia | OTHER |
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It has already been demonstrated that mental imagining of the complex motor act, such as limb lifting, can evoke the activation of the involved motor centres even if it doesn't result in movement due to paresis. Aim of the study: using the navigated brain stimulation system create a new diagnostic model for the differential diagnostics between the vegetative state and the minimally conscious state. If the investigators could get from patient the efferent motor response after a verbal command, his level of conscious should not be defined less than the minimally conscious state.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Vegetative state | Experimental | Patients with the diagnosis of the vegetative state |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Navigated transcranial magnetic brain stimulation | Device | Standard NBS motor mapping using the Eximia TMS stimulator, Nexstim Ltd., Finland. |
|
| Measure | Description | Time Frame |
|---|---|---|
| MEP(motor evoked potential) parameter: latency | within the first minute after a verbal command |
| Measure | Description | Time Frame |
|---|---|---|
| MEP(motor evoked potential) parameter: amplitude | within the first minute after a verbal command | |
| MEP(motor evoked potential) parameter: motor threshold | within the first minute after a verbal command |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Andrey A Belkin, Prof., MD, Phd | Clinical Institute of Brain, Ural State Medical Academy | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Clinical Institute of Brain | Yekaterinburg | Sverdlovsk Oblast | 620102 | Russia |
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| Label | URL |
|---|---|
| Clinical Institute of Brain. Official web-site. | View source |
| Nexstim develops, manufactures and markets Navigated Brain Stimulation devices for clinical use and scientific research. | View source |
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| ID | Term |
|---|---|
| D018458 | Persistent Vegetative State |
| D020521 | Stroke |
| D001930 | Brain Injuries |
| D000070642 | Brain Injuries, Traumatic |
| ID | Term |
|---|---|
| D001925 | Brain Damage, Chronic |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| conscious state | within the first 6 months after NBS mapping |
| D014474 | Unconsciousness |
| D003244 | Consciousness Disorders |
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D002561 | Cerebrovascular Disorders |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D006259 | Craniocerebral Trauma |
| D020196 | Trauma, Nervous System |
| D014947 | Wounds and Injuries |