Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Loss of participants to follow-up
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to identify salivary biomarkers for monitoring cardiometabolic risk in children. The study hypothesis is that a combination of salivary biomarkers will predict the presence of risk factors including impaired fasting glucose, hypertension and dyslipidemia and will reflect changes in these risk factors over time.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Correlation (R values) of salivary biomarkers with blood pressure percentile and serum glucose, HDL, total cholesterol, triglyceride and insulin levels in children | Baseline | |
| Predictive utility (C-statistic) of salivary biomarkers for development of metabolic syndrome during childhood and adolescence | final assessment at age 18 (up to 14 years depending on age of enrollment) |
Not provided
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Children participating in the CARDIAC Boot Camp program at the Robert C. Byrd Clinic in Lewisburg WV
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Kristie G Bridges, PhD | West Virginia School of Osteopathic Medicine | Principal Investigator |
| Jill Cochran, PhD, MSN, RN-C FNP | West Virginia School of Osteopathic Medicine | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| West Virginia School of Osteopathic Medicine | Lewisburg | West Virginia | 24901 | United States |
Not provided
| ID | Term |
|---|---|
| D009765 | Obesity |
| D024821 | Metabolic Syndrome |
| ID | Term |
|---|---|
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
saliva
| D001835 |
| Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D008659 | Metabolic Diseases |