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Imagery Rescripting (IR)is a promising treatment for PTSD in adult survivors of early, chronic, interpersonal trauma (e.g. Smucker & Dancu, 1999). So far, this protocol has not been investigated within a controlled setting with patients with PTSD following early, chronic, interpersonal trauma. The aim of the proposed study is to 1. investigate the efficacy of Imagery Rescripting and 2. check whether the efficacy of Imagery Rescripting can be improved by adding a stabilization phase (Skills training in affective and interpersonal regulation, STAIR) prior to this treatment. In a randomized controlled trial three conditions will be compared:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Imagery Rescripting | Experimental |
| |
| STAIR plus Imagery Rescripting | Active Comparator |
| |
| Wait-list control | No Intervention | Participants from this arm are randomized to the two active conditions after 8 weeks of waiting. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Imagery Rescripting and Reprocessing Therapy | Behavioral | This intervention is comprised of 16 sessions (twice a week) of trauma-focused imagery rescripting |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in Clinician-Administered PTSD Scale (CAPS) at 8 weeks | comparison STAIR vs ImRs vs WL | baseline and 8 weeks |
| Change from Baseline in Posttraumatic Diagnostic Scale (PDS) at 8 weeks | comparison STAIR vs ImRs vs WL | baseline and 8 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in Beck Depression Inventory (BDI)at 8 weeks | baseline and 8 weeks | |
| Change from Baseline in Buss-Durkee Hostility Inventory (BDHI)at 8 weeks | baseline and 8 weeks | |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Merel Kindt, Prof dr | University of Amsterdam | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Amsterdam | Amsterdam | 1018 XA | Netherlands |
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|
| STAIR + Imagery Rescripting | Behavioral | A two-phased treatment. Phase 1 is comprised of 8 (weekly) sessions of Skills Training in Affective and Interpersonal Skills (STAIR). Phase 2 consists of 16 sessions (twice weekly) of trauma-focused imagery rescripting. |
|
| Change from Baseline in Inventory of Interpersonal Problems (IIP)at 8 weeks |
| baseline and 8 weeks |
| Change from Baseline in Dissociation Questionnaire (DIS-Q)at 8 weeks | baseline and 8 weeks |
| Change from Baseline in WHO-Quality of Life(WHO-QL)at 8 weeks | baseline and 8 weeks |
| Change from Baseline in Difficulties in Emotion Regulation Scale (DERS)at 8 weeks | baseline and 8 weeks |
| Change from Baseline in Structured Clinical Interview - Axis I (SCID-1)at 8 weeks | baseline and 8 weeks |
| Posttreatment: Change from Baseline in Clinician-Administered PTSD Scale (CAPS)at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs 24 weeks (WL/STAIR/ImRs) | baseline and max.24 weeks (depending on condition) |
| 12-week follow-up: Change from Baseline in Clinician-Administered PTSD Scale (CAPS) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR/ImRs). | baseline and max. 36 weeks (depending on condition) |
| Post-treatment: Change from Baseline in Posttraumatic Diagnostic Scale (PDS) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR/ImRs) | baseline and max.24 weeks (depending on condition) |
| 12-week fu: Change from Baseline in Posttraumatic Diagnostic Scale (PDS) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR)./ImRs). | baseline and max. 36 weeks (depending on condition) |
| Post-treatment: Change from Baseline in Beck Depression Inventory (BDI) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR). | baseline and max 24 weeks (depending on condition) |
| Change from Baseline in Beck Depression Inventory (BDI) at 20 weeks (ImRs) vs 12-week-fu: 8 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depending on condition) |
| Post-treatment: Change from Baseline in Buss-Durkee Hostility Inventory (BDHI) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR | baseline and max 24 weeks (depending on condition) |
| 12-week FU: Change from Baseline in Buss-Durkee Hostility Inventory (BDHI) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depdending on condition) |
| Post-treatment: Change from Baseline in Inventory of Interpersonal Problems (IIP) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR). | baseline and max 24 weeks (depending on condition) |
| 12-week FU: Change from Baseline in Inventory of Interpersonal Problems (IIP) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depdending on condition) |
| Post-treatment: Change from Baseline in Dissociation Questionnaire (DIS-Q) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR) | baseline and max 24 weeks (depending on condition) |
| 12-week FU: Change from Baseline in Dissociation Questionnaire (DIS-Q) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depdending on condition) |
| Post-treatment: Change from Baseline in WHO-Quality of Life(WHO-QL) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR) | baseline and max 24 weeks (depending on condition) |
| 12-week FU: Change from Baseline in WHO-Quality of Life(WHO-QL) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depdending on condition) |
| Post-treatment: Change from Baseline in Difficulties in Emotion Regulation Scale Post-treatment: Change from Difficulties in Emotion Regulation Scale (DERS) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR) | baseline and max 24 weeks (depending on condition) |
| 12-week FU: Change from Baseline in Difficulties in Emotion Regulation Scale (DERS) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depdending on condition) |
| Post-treatment: Change from Baseline in Structured Clinical Interview - Axis I (SCID-1) at 8 weeks (ImRs) vs 16 weeks (STAIR/ImRs; WL/ImRs) vs. 24 weeks (WL/STAIR) | baseline and max 36 weeks (depdending on condition) |
| 12-week FU: Change from Baseline in Structured Clinical Interview - Axis I (SCID-1) at 20 weeks (ImRs) vs 28 weeks (STAIR/ImRs; WL/ImRs) vs. 36 weeks (WL/STAIR). | baseline and max 36 weeks (depdending on condition) |
| ID | Term |
|---|---|
| D013313 | Stress Disorders, Post-Traumatic |
| ID | Term |
|---|---|
| D040921 | Stress Disorders, Traumatic |
| D000068099 | Trauma and Stressor Related Disorders |
| D001523 | Mental Disorders |
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