This is a clinical study to assess the safety, tolerance and immunogenic response to Gardasil (human papilloma virus (HPV)) and rLP2086 vaccine. Healthy male and female subjects will be randomized into 1 of 3 groups; the trial will be an observer-blinded study to the injection being given; and, vaccinated with either Gardasil and rLP2086 concomitantly, rLP2086 and saline concomitantly, or Gardasil and saline concomitantly. The subjects are adolescent children between the ages of 11 and 17 years old.

Inclusion Criteria:

• Male or female subjects from 11 to 17 years old at the time of they start the study.
• Subject must be healthy which will be determined by obtaining subject's medical history, receiving a physical examination and by judgment of the investigator.

Exclusion Criteria:

• Previous vaccination with any meningococcal serogroup B vaccine.
• Previous vaccination with any HPV vaccine.
• Contraindication to vaccination with Gardasil or any HPV vaccine.