More than 25 percent of the general population suffers from varicose veins, which has a considerable impact on quality of life. Nowadays endovenous treatment modalities for great saphenous incompetence are widely accepted. Mechanochemical endovenous ablation is a new tumescent-less technique, that combines mechanical endothelial damage using a rotating wire with the infusion of a liquid sclerosant. The current study aims at evaluating short and long term outcome after mechanochemical endovenous ablation.

Inclusion Criteria:

• Insufficiency of the GSV
• Ultrasound criteria for endovenous treatment have been met:
• Diameter GSV between 3-12 mm
• No thrombus present at the GSV part to be treated
• Signed informed consent
• Patient willing to present at follow-up visits
• Age > 18 jaar

Exclusion Criteria:

• Patient is unable to give informed consent
• Patient unable to present at all follow-up visits
• Other treatment is more suitable for the treatment of the varicose veins than mechano-chemical ablation
• Pregnancy and breast feeding
• Known allergy/ contra indication for sclerotherapy
• Previous ipsilateral surgical treatment of varicose veins
• Deep venous vein thrombosis in medical history
• Anticoagulant therapy

Patients with insufficiency of the greater saphenous vein will be included.