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| Name | Class |
|---|---|
| Centre de Recherche du Centre Hospitalier de l'Université de Montréal | OTHER |
| Medtronic - MITG | INDUSTRY |
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The purpose of this study is to determine the clinical impact of cerebral and systemic desaturation during liver transplantation and resection on post-operative complications.
This is an observational study. Cerebral and systemic oxymetry (rSO2) using near infrared spectroscopy (NIRS, Invos 5100; Somanet- ics Corporation, Troy, MI) will be performed on all patients with 4 optodes (right and left temporal area, arm and leg). Continuous rSO2 values will be stored on a hard disk with a 15 seconds update within intraoperative period and first 4 hours after the surgery. Desaturation phases (saturation decrease more than 20% of the basal value for more than 15 seconds) will be correlated to operative procedure or events. Postoperative adverse events will be collected. A correlation between desaturation and postoperative adverse events will be done with a multiple linear regression model.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| systemic and cerebral oxymetry | Other | oxymetry measurement using near infrared spectroscopy |
|
| Measure | Description | Time Frame |
|---|---|---|
| define the correlation coefficient between the number of systemic and/or cerebral desaturation phases and the number of postoperative adverse events | from the beginning of anesthesia till 4 hours after the end of the surgery |
| Measure | Description | Time Frame |
|---|---|---|
| define the prevalence of systemic and cerebral desaturation phases during hepatic surgery or transplantation | from the beginning of anesthesia till 4 hours after the end of the surgery | |
| define the correlation coefficient between systemic and/or cerebral desaturation phases and the length of stay in intensive care unit |
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Inclusion Criteria:
Exclusion Criteria:
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patient undergoing hepatic surgery or liver transplantation
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| Name | Affiliation | Role |
|---|---|---|
| Franck Vandenbroucke-Menu, MD | Centre de Recherche du Centre Hospitalier de l'Université de Montréal | Principal Investigator |
| Réal Lapointe, MD-FRCS | Centre de Recherche du Centre Hospitalier de l'Université de Montréal | Principal Investigator |
| André Denault, MD PhD | Centre de Recherche du Centre Hospitalier de l'Université de Montréal | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Centre hospitalier de l'Université de Montréal (CHUM) | Montreal | Quebec | H2X 3J4 | Canada |
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| duration of intensive care stay, an expected average of 4 days |
| validate the equivalence of the systemic and cerebral oxymetry | from the beginning of anesthesia till 4 hours after the end of the surgery |