Tapentadol Versus Oxycodone - a Mechanism-based Treatment Approach in Neuropathic Pain

Phase 4 Study of Tapentadol vs Oxycodone in Neuropathic Pain

The purpose of this study is to elucidate whether the additional mechanism of analgesia, i.e. reuptake inhibition of norepinephrine, of tapentadol leads to a change in different pain signs and symptoms in comparison to oxycodone.

Inclusion Criteria:

• thermal or mechanical hyperalgesia
• chronic neuropathic pain (NRS => 6)

Exclusion Criteria:

• non-specific