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| ID | Type | Description | Link |
|---|---|---|---|
| 2011-A01038-33 | Other Identifier | Afssaps |
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| Name | Class |
|---|---|
| Association pour la Recherche et la Formation en Anesthésie Analgésie Réanimation | OTHER |
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The incidence of postoperative pneumonia after aortic surgery reaches 60%. In experimental lung model, endotracheal tube with taper-shaped cuff has been shown to decrease microaspiration. This effect has never been demonstrated in patients. The investigators hypothesize that use of endotracheal tube with taper-shaped cuff decreases the incidence of postoperative pneumonia in patients after aortic surgery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| endotracheal tube with taper-shaped cuff | Experimental |
| |
| Endotracheal tube with cylindrical-shaped cuff | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Endotracheal tube TaperGuard | Device | Patients are intubated by endotracheal tube with taper-shaped cuff (TaperGuard, Mallinckrodt) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of first episode of postoperative pneumonia after aortic surgery | Within the first 28 days after surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Microaspiration | Day 1 and day 2 | |
| Length of ICU stay | Participants will be followed for the duration of ICU stay, an expected average of 3 weeks | |
| Mortality |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Réanimation polyvalente, Département d'Anesthésie-Réanimation, Groupe Hospitalier Pitié-Salpêtrière | Paris | 75013 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18007268 | Background | Lucangelo U, Zin WA, Antonaglia V, Petrucci L, Viviani M, Buscema G, Borelli M, Berlot G. Effect of positive expiratory pressure and type of tracheal cuff on the incidence of aspiration in mechanically ventilated patients in an intensive care unit. Crit Care Med. 2008 Feb;36(2):409-13. doi: 10.1097/01.CCM.0000297888.82492.31. | |
| 21836137 |
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| Endotracheal tube Hi-Contour Brandt | Device | Patients are intubated by endotracheal tube with cylindrical-shaped cuff (Hi-Contour Brandt, Mallinckrodt) |
|
| Day 28 and day 90 |
| Nseir S, Zerimech F, Fournier C, Lubret R, Ramon P, Durocher A, Balduyck M. Continuous control of tracheal cuff pressure and microaspiration of gastric contents in critically ill patients. Am J Respir Crit Care Med. 2011 Nov 1;184(9):1041-7. doi: 10.1164/rccm.201104-0630OC. |
| 20682571 | Background | Dave MH, Frotzler A, Spielmann N, Madjdpour C, Weiss M. Effect of tracheal tube cuff shape on fluid leakage across the cuff: an in vitro study. Br J Anaesth. 2010 Oct;105(4):538-43. doi: 10.1093/bja/aeq202. Epub 2010 Aug 3. |
| 19557389 | Background | Hortal J, Giannella M, Perez MJ, Barrio JM, Desco M, Bouza E, Munoz P. Incidence and risk factors for ventilator-associated pneumonia after major heart surgery. Intensive Care Med. 2009 Sep;35(9):1518-25. doi: 10.1007/s00134-009-1523-3. Epub 2009 Jun 26. |