The purpose of the study is to compare an acellular epithelial skin substitute with autologous split-thickness skin grafts (STSGs) in deep partial-thickness burns. The objective is to evaluate skin quality and scar formation by using subjective and objective burn scar assessments in order to present valuable data for another additional option of wound coverage in deep partial-thickness burns. The investigators hypothesized that the acellular epithelial skin substitute is at least not inferior to autologous skin grafts.

Inclusion Criteria:

• Patients older than 18 years of age
• verified deep partial-thickness burns
• early tangential excision of burn wound (3-5 days after trauma)

Exclusion Criteria:

• Pregnancy
• ABSI-Score >13
• Active tumor or immune-mediated disease
• Patient refusal