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| ID | Type | Description | Link |
|---|---|---|---|
| 1R01HD070727-01 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | NIH |
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Bridges to the Future: Economic Empowerment for AIDS-Orphaned Children in Uganda, represents the first study that measures medium-term efficacy and cost-effectiveness of a family economic empowerment intervention for AIDS-orphaned children. The usual care provided to AIDS orphans in sub-Saharan Africa consists mainly of informal counseling as well as limited material support (e.g., specifically school lunches, textbooks for the required subjects, and note-books). Given the challenges facing these children and their caregivers, further supports are needed in order to help them successfully make the transition from primary school to secondary school and into adolescence. In the context of resource-poor countries, interventions that improve families' economic capabilities are likely to be particularly consequential. Both theory and prior research indicate that economic instability (including poverty) constitutes one of the primary risk factors for AIDS-orphaned children's risk-taking behaviors (including sexual risk-taking), poor mental health functioning, and poor educational outcomes. Thus, the lack of economic security constitutes an important risk factor for AIDS-orphaned children. Yet, to-date, few interventions aimed at care and support of AIDS-orphaned children have incorporated components to address family-level poverty/economic instability of the children and their caregiving families. Within this context, there is a need for innovative interventions that promote sustainable (more than short-term) economic and behavior change among AIDS-orphaned children and create the supports necessary to sustain these changes.
The overall goal of the proposed research is to evaluate the efficacy and cost-effectiveness of an innovative family-based economic empowerment intervention for AIDS-orphaned children. This will be accomplished via a three-group cluster randomized control trial (RCT). The three groups are: Bridges, Bridges PLUS, and usual care for AIDS-orphaned children. There will be five assessment points: baseline (pretest), 12, 24, 36, and 48-months post-intervention initiation.
The intervention, "Bridges to the Future" (Bridges) will be guided by asset-theory and both Bridges and Bridges PLUS will include the following intervention components tested in the two earlier pilot studies, SEED-Uganda and SUUBI-Uganda: 1) workshops focused on asset building, future planning, and protection from risks; 2) mentors to reinforce learning and build optimism; 3) a Child Development Account (CDA) that can be used for secondary education by the AIDS-orphaned child; and 4) a family income generating/micro-enterprise promotion component for children enrolled in Bridges and Bridges PLUS, and their families.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Bridges | Experimental |
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| Bridges PLUS | Experimental |
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| Usual Care | Other |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bridges | Behavioral | Each child participant in the Bridges Arm will receive the usual care in addition to a Child Development Account (CDA) to be used for secondary education by the AIDS-orphaned child. The CDA will be a matched savings account held in the child's name in a financial institution registered by the Central Bank (Bank of Uganda). The account will be matched with money from the program at a match rate of 1:1. Additionally, participants will receive: 1) twelve 1-2 hour workshops focused on asset building, future planning, and protection from risks; 2) mentorship sessions to reinforce learning and build optimism; and 3) a family income-generating /micro-enterprise promotion component for children enrolled in Bridges and their families. |
| Measure | Description | Time Frame |
|---|---|---|
| Savings and Asset Accumulation | Increased confidence in saving ability and stronger financial stability. Accumulation of formal and informal savings and wealth/assets (e.g. livestock, type of housing, land); and change in attitudes toward saving. | 12-month post-intervention follow-up assessment |
| Educational Achievement | School enrollment and attendance. Educational attainment, plans, and aspirations. Performance on National Primary Leaving Examinations. | 12-month post-intervention follow-up assessment |
| Mental Health Functioning | Degree of hopefulness about the future. Ability to identify specific future goals. Level of mental health functioning. Depressive symptoms. | 12-month post-intervention follow-up assessment |
| Sexual Risk-Taking Behavior | Ability to negotiate safe sex practices. Decreased intentions to engage in sexual risk behavior. Knowledge about and attitude toward HIV/AIDS and other STDs. | 12-month post-intervention follow-up assessment |
| Savings and Asset Accumulation | Increased confidence in saving ability and stronger financial stability. Accumulation of formal and informal savings and wealth/assets (e.g. livestock, type of housing, land); and change in attitudes toward saving. | 24-month post-intervention follow-up assessment |
| Educational Achievement | School enrollment and attendance. Educational attainment, plans, and aspirations. Performance on National Primary Leaving Examinations. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Fred M Ssewamala, PhD | Columbia University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| International Center for Child Health and Asset Development | Masaka | Rakai and Masaka Districts | Uganda |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41878013 | Derived | Nabayinda J, Nabunya P, Bahar OS, Kizito S, Stark L, Namatovu P, Witte SS, Neilands TB, McKay MM, Ssewamala FM. She Is a Guest in My House: Exploring the Barriers to Asset Development and Decision-Making Autonomy Among Young Women in Southern Uganda. J Int Dev. 2025 Oct;37(7):1543-1554. doi: 10.1002/jid.70022. Epub 2025 Sep 8. | |
| 40810883 | Derived | Nabayinda J, Kizito S, Nabunya P, Namuyaba OI, Ssentumbwe V, Bahar OS, Torstein N, McKay M, Ssewamala FM. The Impact of an Economic Empowerment Intervention on Economic Security among AIDS-Orphaned Adolescents in Southern Uganda: the Moderating Role of Depression. AIDS Behav. 2026 Jan;30(1):242-252. doi: 10.1007/s10461-025-04862-0. Epub 2025 Aug 14. |
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| ID | Term |
|---|---|
| D000163 | Acquired Immunodeficiency Syndrome |
| ID | Term |
|---|---|
| D015658 | HIV Infections |
| D000086982 | Blood-Borne Infections |
| D003141 | Communicable Diseases |
| D007239 | Infections |
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|
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| Bridges PLUS | Behavioral | Each child participant in the Bridges PLUS Arm will receive the usual care in addition to a Child Development Account (CDA) to be used for secondary education by the AIDS-orphaned child. The CDA will be a matched savings account held in the child's name in a financial institution registered by the Central Bank (Bank of Uganda). The account will be matched with money from the program at a match rate of 2:1. Additionally, participants will receive: 1) twelve 1-2 hour workshops focused on asset building, future planning, and protection from risks; 2) mentorship sessions to reinforce learning and build optimism; and 3) a family income-generating /micro-enterprise promotion component for children enrolled in Bridges PLUS and their families. |
|
|
| Usual Care | Other | Participants in the usual care condition will receive usual care for AIDS-orphaned children in the study area. This includes: counseling, school lunches, and scholastic materials (textbooks and notebooks). Counseling will be provided by priests in the community (as is currently done). |
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| 24-month post-intervention follow-up assessment |
| Mental Health Functioning | Degree of hopefulness about the future. Ability to identify specific future goals. Level of mental health functioning. Depressive symptoms. | 24-month post-intervention follow-up assessment |
| Sexual Risk-Taking Behavior | Ability to negotiate safe sex practices. Decreased intentions to engage in sexual risk behavior. Knowledge about and attitude toward HIV/AIDS and other STDs. | 24-month post-intervention follow-up assessment |
| Savings and Asset Accumulation | Increased confidence in saving ability and stronger financial stability. Accumulation of formal and informal savings and wealth/assets (e.g. livestock, type of housing, land); and change in attitudes toward saving. | 36-month post-intervention follow-up assessment |
| Educational Achievement | School enrollment and attendance. Educational attainment, plans, and aspirations. Performance on National Primary Leaving Examinations. | 36-month post-intervention follow-up assessment |
| Mental Health Functioning | Degree of hopefulness about the future. Ability to identify specific future goals. Level of mental health functioning. Depressive symptoms. | 36-month post-intervention follow-up assessment |
| Sexual Risk-Taking Behavior | Ability to negotiate safe sex practices. Decreased intentions to engage in sexual risk behavior. Knowledge about and attitude toward HIV/AIDS and other STDs. | 36-month post-intervention follow-up assessment |
| Savings and Asset Accumulation | Increased confidence in saving ability and stronger financial stability. Accumulation of formal and informal savings and wealth/assets (e.g. livestock, type of housing, land); and change in attitudes toward saving. | 48-month post-intervention follow-up assessment |
| Educational Achievement | School enrollment and attendance. Educational attainment, plans, and aspirations. Performance on National Primary Leaving Examinations. | 48-month post-intervention follow-up assessment |
| Mental Health Functioning | Degree of hopefulness about the future. Ability to identify specific future goals. Level of mental health functioning. Depressive symptoms. | 48-month post-intervention follow-up assessment |
| Sexual Risk-Taking Behavior | Ability to negotiate safe sex practices. Decreased intentions to engage in sexual risk behavior. Knowledge about and attitude toward HIV/AIDS and other STDs. | 48-month post-intervention follow-up assessment |
| 33476237 | Derived | Ssewamala FM, Shu-Huah Wang J, Brathwaite R, Sun S, Mayo-Wilson LJ, Neilands TB, Brooks-Gunn J. Impact of a Family Economic Intervention (Bridges) on Health Functioning of Adolescents Orphaned by HIV/AIDS: A 5-Year (2012-2017) Cluster Randomized Controlled Trial in Uganda. Am J Public Health. 2021 Mar;111(3):504-513. doi: 10.2105/AJPH.2020.306044. Epub 2021 Jan 21. |
| 30394541 | Derived | Nabunya P, Padgett D, Ssewamala FM, Courtney ME, Neilands T. Examining the nonkin support networks of orphaned adolescents participating in a family-based economic-strengthening intervention in Uganda. J Community Psychol. 2019 Apr;47(3):579-593. doi: 10.1002/jcop.22139. Epub 2018 Nov 5. |
| D015229 |
| Sexually Transmitted Diseases, Viral |
| D012749 | Sexually Transmitted Diseases |
| D016180 | Lentivirus Infections |
| D012192 | Retroviridae Infections |
| D012327 | RNA Virus Infections |
| D014777 | Virus Diseases |
| D012897 | Slow Virus Diseases |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D007153 | Immunologic Deficiency Syndromes |
| D007154 | Immune System Diseases |