General Practice Research Database Seroquel XR Safety Study

Epidemiology Study to Assess the Safety of a New Slow-release Form of Seroquel (Quetiapine) in the Post-marketing Phase in the UK

The main objective of this observational study is to characterize new users of quetiapine XR as well as new users of other study drugs (i.e. the comparison group) and to quantify the risk of developing newly diagnosed outcomes of interest in new users of quetiapine XR as well as in other study drugs.

Epidemiology study to assess the safety of a new slow-release form of Seroquel (quetiapine) in the post-marketing phase in the UK.

Inclusion Criteria:

• Episodes of new use (>/=1 prescription) of quetiapine XR or other study drugs

Exclusion Criteria:

• Less than two years of recorded history before the start of the marketing of quetiapine XR (or cohort entry date)
• If the duration and dose of the antipsychotic drug cannot be determined