The PK and safety profiles to be examined following a single oral administration of TRK-100STP (120 μg) under fasting conditions to patients with renal impairment and to subjects with normal renal function.

Inclusion Criteria:

• The eGFR 1 day before study drug administration are stipulated as follows.
• Subjects with normal renal function : ≥90
• Patients with mild renal impairment : ≥60 to <90
• Patients with moderate renal impairment : ≥30 to <60
• Patients with severe renal impairment : ≥15 to <30

Exclusion Criteria:

• Patients on dialysis
• Patients who have a history of undergoing renal transplantation
• Patients with diabetes mellitus