OxIGen: Oxford Imagery Generation: Investigating the Effects of an Internet Based Computer Program in Depression

OxIGen: Oxford Imagery Generation: Investigating the Effects of an Internet Based Computer Program in Depression

This research study is designed to investigate the effects of an online computer program, called OxIGen (Oxford Imagery Generation), on thinking style and mood in depression. The OxIGen program will be delivered online over four weeks and with follow-up at one, three and six months. This will inform potential future development of this computerized task into an online intervention to modify negative thinking styles in depression.

Inclusion Criteria:

• Willing and able to give consent to the study
• Male or Female, aged between 18 and 65 years
• Current Major Depressive Episode (assessed by semi-structured clinical interview)
• Access to internet in order to complete the online program
• Able to travel to research centre for assessment appointments
• Fluent in written and spoken English

Exclusion Criteria:

• Meets criteria for current psychotic disorder
• History of mania or hypomania as assessed by semi-structured clinical interview, or has elsewhere received a diagnosis of Bipolar disorder
• Antidepressant medication begun or changed in dosage during last month
• Meets criteria for current substance abuse disorder
• Involved in other current treatment trials
• Currently receiving psychological therapy