Laparoscopic Gastrectomy for Advanced Gastric Cancer

Laparoscopic Gastrectomy for Advanced Gastric Cancer

Although laparoscopic gastrectomy (LG) is widely used for the treatment of early gastric cancer, there have been few reports of the efficacy of LAG in the management of advanced gastric cancer(AGC). The aim of this study is to evaluate the surgical outcomes and oncologic safety of laparoscopic gastrectomy for AGC.

Prospective phase II clinical trial to evaluate technical and oncological safety of LG for AGC

LG procedure for AGC:

D2 lymphadenectomy Total omentectomy for tumor with serosa exposure under laparoscopic exploration

Primary end point: 3 year disease free survival secondary end point: postoperative outcomes, morbidity and mortality, 3,5 and 7 year overall survival, Quality of life, recurrence pattern

Study duration: 7 years(enrollment: 4year, follow-up: 3year)

Inclusion Criteria:

• Age 20-80
• informed consent
• no other malignancies
• cT2N0-cT3N2 according to JGCA 2nd edition
• ASA score<3

Exclusion Criteria:

• distant metastasis(P1 or M1) under laparoscopic exploration
• Conglomerated N2
• early gastric cancer in permanent pathologic report