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The propose of this study is to determine the effect of intravenous fentanyl prior the end of surgery on the incidence and severity of EA in pediatric patient.
Emergence agitation (EA) is a common self limiting problem after emerging from general anesthesia (GA) especially in pediatric patients. The incidence of EA in Thai population, the incidences of EA 43.2% in pediatric patients aged between 2-9 years. There have been many studies tried to reduce the incidence of EA in various ways such as Preoperative anxiety reduction method and medication. Premedication, Sedative drugs and narcotic drugs were used to reduce the incidence of EA.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| fentanyl group | Active Comparator | First arm: intervention group. Patient in this group received fentanyl 1 mcg/kg (concentration 10mcg/ml) intravenous route 15 minutes before the end of surgery. |
|
| controlled group | Placebo Comparator | patient in this group received NSS 0.1 ml/kg 15 minutes before the end of surgery |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| fentanyl | Drug | In intervention group patient received fentanyl 1 mcg/kg intravenous 15 minutes before the end of surgery. |
|
| Measure | Description | Time Frame |
|---|---|---|
| the incidence of emergence agitation | pt was observed since emerging from anesthesia up to 60 minutes |
| Measure | Description | Time Frame |
|---|---|---|
| severity of emergence agitation | pt was observed since emerging from anesthesia up to 60 minutes | |
| adverse effect from intravenous fentanyl prior the end of surgery | pt was observed since emerging from anesthesia upto 60 minutes |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Faculty of Medicine, Prince of Songkla University | Hat Yai | Changwat Songkhla | 90110 | Thailand |
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| ID | Term |
|---|---|
| D011595 | Psychomotor Agitation |
| D000071257 | Emergence Delirium |
| ID | Term |
|---|---|
| D020820 | Dyskinesias |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D011596 | Psychomotor Disorders |
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| ID | Term |
|---|---|
| D005283 | Fentanyl |
| ID | Term |
|---|---|
| D010880 | Piperidines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
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| NSS | Drug | Patient in this group received NSS (0.1ml/kg)intravenous route 15 minutes before the end of surgery. |
|
| post operative pain | pt was observed since emerging from anesthesia up to 60 minutes |
| D019954 |
| Neurobehavioral Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D000096762 | Aberrant Motor Behavior in Dementia |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D003693 | Delirium |
| D003221 | Confusion |
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |