A Study to Measure Needle Bending and Changes in Prostate Shape During a Prostate Seed Implant

Quantifying Needle Deflection and Tissue Deformation in Transperineal Interstitial Permanent Prostate Brachytherapy: A Basis for Development of Next-Generation Implant Technique

Prostate brachytherapy is an effective treatment option for men with localized prostate cancer, with excellent cure rates and a favorable toxicity profile. With the current needle insertion technique, seed placement inaccuracy is primarily caused by needle deflection and soft tissue deformation, which both occur during the brachytherapy operation. This study will accrue 20 patients undergoing prostate brachytherapy implants and acquire a series of ultrasound images, video clips and one CT scan.

Inclusion Criteria:

• Prostate cancer
• Treated with prostate brachytherapy at the Cross Cancer Institute
• Low and intermediate risk prostate cancer
• ambulatory patients
• stable medical condition
• Over 18 years of age
• Capable of giving informed consent

Exclusion Criteria:

• Any hormonal therapy