Observational Study on Rotavirus Gastroenteritis Epidemiology, Impact of Lyophilised vs. Liquid Formulation of Rotarix™

Observational, Ecological, Database Study on Epidemiology of Hospitalisations With Rotavirus Gastroenteritis Confirmed in Children Aged ≤5 Years, and Any Impact in the Change From Lyophilised to Liquid Formulation of Rotarix™, in Belgium

The aim of this study is to monitor any impact in the change from the lyophilised formulation to the liquid formulation of the Rotarix™ vaccine on hospitalisations for rotavirus gastroenteritis. This is planned to be assessed by comparing trends of hospitalisations due to laboratory confirmed rotavirus gastroenteritis in children <=5 years of age, before and after introduction of the liquid formulation of the vaccine in Belgium.

Inclusion Criteria:

All subjects must satisfy ALL the following criteria at study entry:

• Child aged ≤5 years with opportunity to receive lyophilised or liquid formulation of Rotarix™;
• Hospitalised at one of the participating centres in Belgium;
• A stool sample has been provided for a rotavirus detection test during the study period;
• Laboratory test result of rotavirus is available.

Exclusion Criteria:

• None.