Capturing Parkinson's Disease Medication Side Effects During Daily Activities

Phase I Study: Monitoring Levodopa-Induced Dyskinesia Using Accelerometer & Gyroscope-based Motion Detection System

The purpose of the study is to test whether body-worn wireless motion sensors can measure dyskinesias (involuntary movements caused by medications) in individuals with Parkinson disease (PD) independent of voluntary activity being performed and other PD motor symptoms (e.g. tremor).

Inclusion Criteria:

• Clinical diagnosis of probable or definite idiopathic Parkinson Disease with motor fluctuations that include dyskinesias after taking their usual dose of levodopa/carbidopa

Exclusion Criteria:

• Antipsychotic medications (including quetiapine and clozapine)
• Coexisting neurologic disease such as stroke or dementia
• Lacking capacity for informed consent
• Residing in a nursing home
• comorbid non-neurologic illnesses that impacts the ability to perform the study tasks
• Implantable defibrillators