Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| National Science and Technology Council, Taiwan | OTHER_GOV |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose of this study is to evaluate the effect of "combined probiotics" to improve the gastrointestinal function and intestinal bacteria flora
Probiotics were known to improve gastrointestinal function before. This is a single-blind placebo control clinical study. We will perform gastrointestinal function questionnaire and collect stool as baseline data before the study (0-week). Then healthy subjects will be randomized to two groups.
Experimental: probiotics 1 pack bid for 3 weeks. Probiotics : (AB-kefir):Lactobacillus acidophilus,Bifidobacterium longum,Lactobacillus paracasei,Lactobacillus rhamnosus,Lactobacillus fermentum,Streptococcus thermophilus,Lactobacillus helveticus,Kluyveromyces fragilis. Other components include starch,oligosaccharide,yeast powder, superior standard spice, calcium pantothenate, VitB1, VitB12, biotin and folic acid.
Placebo group: placebo 1 pack bid for 3 weeks. Placebo: Except the probiotics (AB-kefir),the other components are the same with study group.
Then gastrointestinal function questionnaire and stool collection will be performed at the end of 1st, 2nd, 3rd, and 4th weeks after starting the study.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| probiotics | Experimental | 1 pack bid use for 3 weeks |
|
| Placebo | Placebo Comparator | placebo 1pack bid for 3 weeks |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| probiotics | Dietary Supplement | probiotics 1 pack (2g) bid for three weeks |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes of gastrointestinal function after probiotics use | Changes of gastrointestinal function, such as constipation, abdominal distension and appetite after proiotics and placebo use. | 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Changes of intestinal bacteria flora after probiotics use |
|
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ming-Cheng Wang, MD | Contact | 886-6-2353535 | 2594 | wangmc@mail.ncku.edu.tw |
| An-bang Wu, MD | Contact | 886-6-2353535 | 2594 | anbang@mail.ncku.edu.tw |
| Name | Affiliation | Role |
|---|---|---|
| Ming-Cheng Wang, MD | National Cheng-Kung University Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| National Cheng Kung University Hospital | Tainan | Taiwan |
Not provided
| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| 28 days |
| D019602 |
| Food and Beverages |