The purpose of this study is to compare the ability of Aquacel® Ag and Mepilex® Border Ag to manage bioburden in leg ulcers over a two week study period.

Inclusion Criteria:

• Aged 18 years or over
• Willing and able to provide written informed consent
• Leg ulcer will be of size ranging between 10 cm2 - 40 cm2 with moderate or heavy exudate
• Leg ulcer will exhibit at least 2 of the 4 following clinical signs: pain between 2 dressing changes, peri-ulcer skin erythema, oedema, foul odour

Exclusion Criteria:

• Known skin sensitivity to any component of the products being tested
• Subjects who have had current local or systemic antibiotics and/or topical antimicrobials applied in the week prior to inclusion
• Depth of ulcer classified as superficial (not involving dermis) or deep (exposing muscle and tendon)
• Any other medical condition which, according to the investigator, justifies the subject's exclusion from the study
• Participated in a clinical study within the past 30 days