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| Name | Class |
|---|---|
| Suikerstichting Nederland (Baarn) | UNKNOWN |
The objective of the current study is to determine the acute effect of a glucose drink and a sacharose drink compared to a placebo on cognitive performance in elderly with light memory complaints. The investigators expect that the sugar containing drinks will improve memory and attentional functions. Furthermore, blood glucose response will be measured.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Drink with 50 g glucose | Active Comparator | The glucose drink contains 50 g of glucose soluted in 250 ml of water and lemon juice. |
|
| Drink with 100 gram of sacharose | Active Comparator | The sacharose drink contains 100 g of sacharose soluted in 250 ml of water and lemon juice. |
|
| Placebo with sweeteners | Placebo Comparator | The placebo contains a mixture of artificial sweeteners in order to have the same sweetness and appearance of the test drinks (the glucose drink and the sacharose drink). |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| glucose | Dietary Supplement | The effect of a glucose solution on cognitive performance will be measured. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Performance on the paired associate recall test | Cognitive performance will be assessed by several sensitive tests. Power is calculated on the paired associate recall test, but also several other cognitive performance test focusing on memory, attention and reaction time will be performed | cognitive tests will start 15 minutes after ingestion of the intervention product |
| Measure | Description | Time Frame |
|---|---|---|
| Mood | Mood will be measured by the POMS, after consuming the test drink, and after completing the congitive tests. | within 15 minutes after consuming the test drink and after completing the cognitive tests (within 90 minutes after consuming the test drink) |
| Blood glucose response |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Wageningen University | Wageningen | Gelderland | 6703 HD | Netherlands |
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| ID | Term |
|---|---|
| D000092862 | Psychological Well-Being |
| ID | Term |
|---|---|
| D010549 | Personal Satisfaction |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D005947 | Glucose |
| D013395 | Sucrose |
| D000073893 | Sugars |
| ID | Term |
|---|---|
| D006601 | Hexoses |
| D009005 | Monosaccharides |
| D002241 | Carbohydrates |
| D004187 | Disaccharides |
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| sacharose | Dietary Supplement | The effect of a sacharose solution on cognitive performance will be measured. |
|
| Placebo | Dietary Supplement | The effect of a placebo drink with sweeteners on cognitive performance will be measured. |
|
Blood glucose will be measured at five time points, at t=0, after 15 minutes, 30, 60 and 90 minutes. |
| from baseline till 90 minutes after consuming the drink |
| Plasma insulin levels | One venapunction will be carried out at baseline to measure plasma insulin levels. | At t= -15 minutes, before consuming the test drink |
| D009844 |
| Oligosaccharides |
| D011134 | Polysaccharides |