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Too few of the invited subjects wanted to participate
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Aim: to examine caries occurrence in children who ten years ago received a mixture of probiotics during infancy.
Hypothesis: the administration of probiotics during infancy has no effect on future dental health.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Probiotics in milk formula | Active Comparator | B. lactis BB-12 and L. rhamnosus GG delivered in milk formula during the first year of infancy |
|
| Control milk formula | Placebo Comparator | The children received milk formula with no probiotics |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotics in infant milk formula | Dietary Supplement | Probiotic infgant milk formula administered during the forst year of life |
|
| Measure | Description | Time Frame |
|---|---|---|
| Caries occurence | 10 years |
| Measure | Description | Time Frame |
|---|---|---|
| Oral microbial colonization | 10 years |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Erika M Isolauri, Professor | University of Turku | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Turku | Turku | Finland | 20520 | Finland |
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| ID | Term |
|---|---|
| D003731 | Dental Caries |
| ID | Term |
|---|---|
| D017001 | Tooth Demineralization |
| D014076 | Tooth Diseases |
| D009057 | Stomatognathic Diseases |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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|
| D019602 |
| Food and Beverages |