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Lack of eligible patients and study staff
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| Name | Class |
|---|---|
| The Swedish Research Council for Environment, Agricultural Sciences and Spatial Planning (FORMAS) | OTHER_GOV |
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Probiotics and fruit fibre are given for 12 weeks to patients with fatty liver disease.
The hypothesis is that probiotic bacteria and fruit fibre affect the gut microbial composition in a positive manner. The improved ecological system is believed to contribute to improved liver health and thereby counteract fatty liver disease.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Probiotics and fruit fibre | Experimental | Probiotics and fruit fibre |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Probiotics and fruit fibre | Dietary Supplement | probiotics and fruit fibre |
|
| Measure | Description | Time Frame |
|---|---|---|
| Improved and normalized liver status | normalized concentrations of liver enzymes in plasma. Magnetic resonanse imaging (compared to magnetic resonanse imaging before intervention) will also be used in the investigation of improved liver status. | after 12 weeks intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in the gut bacterial flora | Changes and differences of the gut bacterial flora will be addressed in detail, e.g. changes in concentration of specific bacterial groups (e.g. Lactobacillus) before and after the intervention period. | after 12 weeks intervention |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Skåne University Hospital | Malmö | Sweden |
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| ID | Term |
|---|---|
| D005234 | Fatty Liver |
| D009765 | Obesity |
| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D004066 | Digestive System Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
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| ID | Term |
|---|---|
| D019936 | Probiotics |
| ID | Term |
|---|---|
| D019587 | Dietary Supplements |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
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| D009748 |
| Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D019602 |
| Food and Beverages |