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The purpose of this study is to determine whether a daily use of a Kneipp hot cataplasm with caraway oil is effective in the treatment of abdominal pain and complaints caused by Irritable bowel syndrome.
see above.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Hot Cataplasm with Caraway Oil | Experimental |
| |
| Hot Cataplasm with Olive oil | Active Comparator |
| |
| Cold cataplasm with Olive oil | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| caraway oil | Drug | essential oil, Carum carvi, 2% dissolved in olive oil, 1 teaspoon with caraway oil used externally as inunction together with a hot cataplasm |
|
| Measure | Description | Time Frame |
|---|---|---|
| Irritable Bowel Syndrome - Symptom Severity Score | IBS-SSS (Francis 1997) | at T2 (Day 21) |
| Measure | Description | Time Frame |
|---|---|---|
| Frequency of abdominal discomfort/Pain | Diary, daily rating of pain | last week of treatment (days 14-21) |
| Intensity of abdominal discomfort/Pain | Daily rating of pain intensity on a 100mm Visual analogue scale, pain diary |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jost Langhorst, MD, Prof | University Duisburg-Essen, Chair of Integrative Gastroenterology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Klinik für Naturheilkunde und Integrative Medizin | Essen | 45276 | Germany |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 26044145 | Result | Lauche R, Janzen A, Ludtke R, Cramer H, Dobos G, Langhorst J. Efficacy of Caraway Oil Poultices in Treating Irritable Bowel Syndrome--A Randomized Controlled Cross-Over Trial. Digestion. 2015;92(1):22-31. doi: 10.1159/000398790. Epub 2015 Jun 5. |
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| ID | Term |
|---|---|
| D043183 | Irritable Bowel Syndrome |
| ID | Term |
|---|---|
| D003109 | Colonic Diseases, Functional |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |
| D005767 | Gastrointestinal Diseases |
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| ID | Term |
|---|---|
| C104525 | caraway oil |
| D000069463 | Olive Oil |
| ID | Term |
|---|---|
| D004042 | Dietary Fats, Unsaturated |
| D004041 | Dietary Fats |
| D005223 | Fats |
| D008055 | Lipids |
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| Olive oil | Drug | 1 teaspoon with caraway oil used externally as inunction together with a hot or cold cataplasm as assigned |
|
| last week of treatment (days 14-21) |
| Quality of life | measured with the EQ-5D | T2 (Day 21) |
| Quality of life - ibs specific | measured with the IBS-QOL (Patrick, 1998) | T2 (day 21) |
| Depression and Anxiety | HADS questionnaire (Hermann, 1995) | T2 (day 21) |
| Global improvement | Question on global improvement: How have your symptomes changed compared to the last week: from much worse to much better on a 7-point scale | At day 7, 14 and 21 |
| h-BD2 | h-BD2 laboratory findings | T2 (day 21) |
| Adequate Relief Score | Adequate Relief Score (Mangel, 1998) | at day 7, 14, 21 |
| D004066 | Digestive System Diseases |
| D005224 |
| Fats, Unsaturated |
| D010938 | Plant Oils |
| D009821 | Oils |
| D005502 | Food |
| D000066888 | Diet, Food, and Nutrition |
| D010829 | Physiological Phenomena |
| D019602 | Food and Beverages |