Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The primary purpose of this study is to determine whether a 12 week Pilates based core stability training programme is effective in improving balance, mobility and balance confidence in ambulant individuals with Multiple Sclerosis (MS).
The primary purpose of this study is to determine whether a 12 week Pilates based core stability training programme is effective in improving balance, mobility and balance confidence in ambulant individuals with Multiple Sclerosis (MS). The secondary aim is to determine the relative effectiveness of this 12 week Pilates based core stability training programme compared to a standardised physiotherapy exercise programme. Finally we intend to explore the underlying mechanisms of change associated with these exercise interventions by directly measuring changes in muscle thickness and activation in the deep abdominal core stabilising muscles of a sub-set of participants.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Core Stability Training | Experimental |
| |
| Relaxation | Placebo Comparator |
| |
| Standard Physiotherapy Exercises | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Standard Physiotherapy Exercises | Other | Individualised face to face training sessions, delivered over 12 weeks, plus an individualised 15-minute daily home exercise programme will be provided. This will be undertaken by a neurological physiotherapist. The exercises will comprise a standardised programme of simple physiotherapy exercises which aim to improve trunk and pelvic stability, lower limb muscle length and strength, and balance and control of movement, as described by Barrett et al [2009]. Exercises will be progressed in response to the abilities of the individual. Each participant will receive a workbook with written and diagrammatic instructions describing their home exercise programme. |
| Measure | Description | Time Frame |
|---|---|---|
| Change in 10 metre timed walk (10MTW) | baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks ( one month follow-up) |
| Measure | Description | Time Frame |
|---|---|---|
| Change in Functional Reach - forwards and lateral | baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks ( one month follow-up) | |
| Change in Visual Analogue Scale (10 point) to determine "Difficulty in carrying a drink when walking". |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Jennifer Freeman | University of Plymouth | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Merlin Centre, Bradbury House, Hewas water | St Austell | Cornwall | PL26 7JF | United Kingdom | ||
| Devon NHS Trust |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20699285 | Background | Freeman JA, Gear M, Pauli A, Cowan P, Finnigan C, Hunter H, Mobberley C, Nock A, Sims R, Thain J. The effect of core stability training on balance and mobility in ambulant individuals with multiple sclerosis: a multi-centre series of single case studies. Mult Scler. 2010 Nov;16(11):1377-84. doi: 10.1177/1352458510378126. Epub 2010 Aug 10. | |
| 22480437 |
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Sep 3, 2015 | |
| Reset | Oct 2, 2015 | |
| Release | Oct 25, 2017 | |
| Reset | Jul 27, 2018 |
Not provided
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Sep 3, 2015 | Oct 2, 2015 | |||
| Oct 25, 2017 |
| ID | Term |
|---|---|
| D009103 | Multiple Sclerosis |
| ID | Term |
|---|---|
| D020278 | Demyelinating Autoimmune Diseases, CNS |
| D020274 | Autoimmune Diseases of the Nervous System |
| D009422 | Nervous System Diseases |
| D003711 | Demyelinating Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D026741 | Physical Therapy Modalities |
| ID | Term |
|---|---|
| D013812 | Therapeutics |
| D012046 | Rehabilitation |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
|
| Core Stability Training | Other | Individualised face to face training sessions, delivered over 12 weeks, plus an individualised 15-minute daily home exercise programme will be provided. This will be undertaken by a neurological physiotherapist with experience in the delivery of core stability training to people with MS. Exercises will be progressed in response to the abilities of the individual. Each participant will receive a workbook with written and diagrammatic instructions describing their home exercise programme. |
|
|
| Relaxation | Other | Three face to face individualised relaxation sessions, provided at 4 weekly intervals, plus a 15-minute home programme based around an audio relaxation CD. Weekly telephone contact / support will be provided. |
|
|
| baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks ( one month follow-up) |
| Change in Activities-specific Balance Confidence (ABC) Scale | baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks (one month follow-up) |
| Change in Multiple Sclerosis 12-item Walking Scale | baseline (pre intervention), 12 weeks (immediately post intervention), 16 weeks (one month follow-up) |
| Newton Abbot |
| Devon |
| TQ12 2SL |
| United Kingdom |
| University Of Plymouth, School of Health Professions | Plymouth | Devon | PL6 9BH | United Kingdom |
| Tavistock Community Hospital | Spring Hill, Tavistock | Devon | PL19 8LD | United Kingdom |
| Lanarkshire NHS Trust | Cumbernauld | North Lanarkshire | G671BP | United Kingdom |
| South Tees NHS Trust | Middlesbrough | South Tees | TS3BW | United Kingdom |
| University College London Hospital Trust | London | WC1 N3BG | United Kingdom |
| Freeman J, Fox E, Gear M, Hough A. Pilates based core stability training in ambulant individuals with multiple sclerosis: protocol for a multi-centre randomised controlled trial. BMC Neurol. 2012 Apr 5;12:19. doi: 10.1186/1471-2377-12-19. |
| Background | Fox et al. (2013) Pilates based core stability training in ambulant individuals with multiple sclerosis: a multicentre, blinded, randomised, placebo controlled trial Way Ahead 2014;18(1):6-8 http://www.mstrust.org.uk/professionals/information/wayahead/articles/18012014_03.jsp |
| Jul 27, 2018 |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |