Hibiscus Sabdariffa and Centella Asiatica in the Treatment of Anemia by Iron Deficiency

Prevalence of Genetic Polymorphisms of DMT1 and Ferroportin Enzymes in Adults With Anemia by Iron Deficiency, and Its Influence on the Efficacy of Conventional and Herbal Treatments

The study aims to investigate the prevalence of genetic polymorphisms in adults with iron deficiency and anemia, and the responses to two different treatments: iron sulphate and a composite herbal medicine (Hibiscus sabdariffa plus Centella asiatica). The main outcome will be hemoglobin, measured before and after 6 weeks.

Inclusion Criteria:

• Age > 18 y and < 50 y
• A diagnostic of iron deficient anemia

Exclusion Criteria:

• Severe anemia
• Treatment interruption for more than 25% of the 6 weeks
• New onset severe adverse symptoms or events
• Patient's request