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| Name | Class |
|---|---|
| Hadassah Medical Organization | OTHER |
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Phenotype characterization of shortness of breath of pediatric emergency room patients by objective wheeze and cough monitoring improves diagnostic and severity assessment accuracy and correlates with overall patient outcomes.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group 1: Patients ages 0 - 3 | |||
| Group 2: Patients ages 3 - 7 | |||
| Group 3: Patients ages 7 - 15 |
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| Measure | Description | Time Frame |
|---|---|---|
| increase or decrease of WheezeRate (the proportion of wheezing in the respiratory cycle) | Characterize the dynamic pattern of wheeze rate (increase or decrease by 50% or unchanged) within 30 minutes of onset of therapy, and to correlate pattern to clinical diagnoses, severity assessment (accessory muscle use, oxygen saturation, inspiratory/expiratory ratio, severity of wheezing), and outcome (admission versus discharge). | Duration (from beginning to end) of emergency department stay. On average, 3 hours. |
| Measure | Description | Time Frame |
|---|---|---|
| cough count (increase or decrease by more then 1 cough event or unchanged) in response to treatment | cough count (increase or decrease by more then 1 cough event or unchanged) in response to treatment and to correlate pattern to clinical diagnoses, severity assessment (accessory muscle use, oxygen saturation, inspiratory/expiratory ratio, severity of wheezing), and outcome (admission versus discharge). |
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Inclusion Criteria:
patient is admitted to the ER with shortness of breath
patient management is according to standardized protocols used in Hadassah Mt. Scopus pediatric emergency department including:
ages 0 - 15
patient's parent/guardian is able to comprehend and give informed consent for participating in the study
Exclusion Criteria:
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Pediatric emergency room patients ages 0 - 15 with shortness of breath upon arrival at the hospital
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Noam Gavriely, MD PhD | Contact | +972 54 466 1337 | noam@karmelsonix.com | |
| Ezekiel Balouka, MSc | Contact | +972 52 312 1098 | ezekiel@karmelsonix.com |
| Name | Affiliation | Role |
|---|---|---|
| Eitan Kerem, Prof. | Hadassah Medical Center Mt. Scopus, Jerusalem, Israel | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hadassah Medical Center Mt. Scopus | Jerusalem | Israel |
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| ID | Term |
|---|---|
| D001249 | Asthma |
| D001988 | Bronchiolitis |
| ID | Term |
|---|---|
| D001982 | Bronchial Diseases |
| D012140 | Respiratory Tract Diseases |
| D008173 | Lung Diseases, Obstructive |
| D008171 | Lung Diseases |
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| Duration (from beginning to end) of emergency department stay. On average, 3 hours. |
| D012130 |
| Respiratory Hypersensitivity |
| D006969 | Hypersensitivity, Immediate |
| D006967 | Hypersensitivity |
| D007154 | Immune System Diseases |
| D001991 | Bronchitis |
| D012141 | Respiratory Tract Infections |
| D007239 | Infections |