The purpose of this registry is to create a database that collects clinical data to improve knowledge about primary hyperparathyroidism.

This will be a multi-institutional prospective study in which patients that have undergone parathyroidectomy with intra-operative PTH assessment. The success of minimally invasive parathyroidectomy without and with intra-operative PTH will be assessed for each patient. Success for exploration without intra-operative PTH will be defined as directed exploration with detection of an abnormal parathyroid in the location suggested by imaging. Success with intra-operative PTH will be defined as per standard protocols (50% or > decrease in intra-operative PTH following excision).

Inclusion Criteria:

• Adult individuals (male and female) who have a personal diagnosis/history of primary hyperparathyroidism.
• Age 19 or greater.
• Patients who are seen and treated surgically at UNMC's Department of Otolaryngology- Head Neck Surgery .
• Able to provide informed consent.

Exclusion Criteria:

-No history of primary hyperparathyroidism

Otolaryngology, Head and Neck Surgery clinic patients